human SMCHD1 shRNA silencing AAV

Name
AAV-h-SMCHD1-shRNA

Cat No
shAAV-233911

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human SMCHD1.

shAAV-233911

AAV-h-SMCHD1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SMCHD1 (structural maintenance of chromosomes flexible hinge domain containing 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

BAMS; FSHD2; SMC hinge domain-containing protein 1; structural maintenance of chromosomes flexible hinge domain-containing protein 1

Description (eCommerce)

SmcHD1 (structural maintenance of chromosomes flexible hinge domain-containing protein 1) has been shown to play a role in the maintenance of X-inactivation and the hypermethylation of CpG islands associated with inactive X.

Description (Vector)

SMCHD1 encodes a protein which contains a hinge region domain found in members of the SMC (structural maintenance of chromosomes) protein family.

Gene ID

23347

Gene Name (eCommerce)

structural maintenance of chromosomes flexible hinge domain containing 1

Gene Name (Vector)

structural maintenance of chromosomes flexible hinge domain containing 1

Gene Symbol

SMCHD1

HGNC ID

HGNC:29090

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

6018

ORF Size (bp)

6018 bp

Protein Name (eCommerce)

Structural maintenance of chromosomes flexible hinge domain-containing protein 1

RefSeq ID

NM_015295

RefSeq Synonyms

NM_015295, BC035774,

Research Areas

Chromatin Remodeling

Research Areas (Faceted)

cell_biology,genetics

Species

human

Target Sentence

UniProt ID (eCommerce)

A6NHR9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.