human DNAH6 shRNA silencing AAV

Name
AAV-h-DNAH6-shRNA

Cat No
shAAV-233875

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human DNAH6.

shAAV-233875

AAV-h-DNAH6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DNAH6 (dynein axonemal heavy chain 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Dnahc6; DNHL1; HL-2; HL2

Description (Vector)

Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. Two major classes of dyneins, axonemal and cytoplasmic, have been identified. DNAH6 is an axonemal dynein heavy chain (DHC) (Vaughan et al., 1996 (PubMed 8812413)).(supplied by OMIM, Mar 2008)

Gene ID

1768

Gene Name (Vector)

dynein axonemal heavy chain 6

Gene Symbol

DNAH6

HGNC ID

HGNC:2951

ORF Size (aa)

1656

ORF Size (bp)

1656 bp

RefSeq ID

NM_001370

RefSeq Synonyms

NM_001370, BC113424, BC015442,

Species

human

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.