human CCDC88C shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CCDC88C.
shAAV-233671
AAV-h-CCDC88C-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CCDC88C (coiled-coil domain containing 88C). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Coiled-coil domain-containing protein 88C; DAPLE; Dvl-associating protein with a high frequency of leucine residues; hDaple; HKRP2; hook-related protein 2; HYC1; KIAA1509; protein Daple; SCA40; spinocerebellar ataxia 40
Description (eCommerce)
Daple (Dvl-associating protein with a high frequency of leucine residues) is a negative regulator of the canonical Wnt signaling pathway and acts downstream of DVL to inhibit CTNNB1/Beta-catenin stabilization [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9P219].
Gene ID
440193
Gene Name (eCommerce)
coiled-coil domain containing 88C
Gene Name (Vector)
coiled-coil domain containing 88C
Gene Symbol
CCDC88C
HGNC ID
HGNC:19967
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1521
ORF Size (bp)
1521 bp
Protein Name (eCommerce)
Protein Daple
RefSeq ID
NM_001080414
RefSeq Synonyms
NM_001080414, BC035914,
Research Areas
Cytoskeleton,Signal Transduction,Wnt Signaling
Research Areas (Faceted)
cell_biology,signal_transduction
Species
human
Target Sentence
Daple (Dvl-associating protein with a high frequency of leucine residues) is a negative regulator of the canonical Wnt signaling pathway and acts downstream of DVL to inhibit CTNNB1/Beta-catenin stabilization [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9P219].
UniProt ID (eCommerce)
Q9P219
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.