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human CDH23 shRNA silencing AAV

Name 
AAV-h-CDH23-shRNA
Cat No 
shAAV-233576
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CDH23.

shAAV-233576
AAV-h-CDH23-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CDH23 (cadherin related 23). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CDHR23; USH1D
Description (Vector)
CDH23 is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Alternative splice variants encoding different isoforms have been described.
Gene ID
64072
Gene Name (Vector)
cadherin related 23
Gene Symbol
CDH23
HGNC ID
HGNC:13733
ORF Size (aa)
3186
ORF Size (bp)
3186 bp
RefSeq ID
NM_022124
RefSeq Synonyms
NM_052836, NM_022124, NM_001171936, NM_001171935, NM_001171934, NM_001171933, NM_001171932, NM_001171931, NM_001171930, BC032581,
Species
human

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.