human A2LD1 shRNA silencing AAV

Name
AAV-h-A2LD1-shRNA

Cat No
shAAV-233323

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human GGACT.

shAAV-233323

AAV-h-A2LD1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GGACT (gamma-glutamylamine cyclotransferase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

A2LD1

Description (Vector)

A2LD1 aids in the proteolytic degradation of crosslinked fibrin by breaking down isodipeptide L-gamma-glutamyl-L-epsilon-lysine, a byproduct of fibrin degradation. The reaction catalyzed by the encoded gamma-glutamylaminecyclotransferase produces 5-oxo-L-proline and a free alkylamine. Two transcript variants encoding the same protein have been found for this gene.

Gene ID

87769

Gene Name (Vector)

gamma-glutamylamine cyclotransferase

Gene Symbol

GGACT

HGNC ID

HGNC:25100

ORF Size (aa)

462

ORF Size (bp)

462 bp

RefSeq ID

NM_033110

RefSeq Synonyms

NM_033110, NM_001195087, BC001077,

Species

human

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.