human DYX1C1 shRNA silencing AAV

Name 
AAV-h-DYX1C1-shRNA
Cat No 
shAAV-232660
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human DYX1C1.

shAAV-232660
AAV-h-DYX1C1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DYX1C1 (dyslexia susceptibility 1 candidate 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CILD25; DNAAF4; DYX1; DYXC1; EKN1; RD
Description (Vector)
DYX1C1 encodes a tetratricopeptide repeat domain-containing protein. The encoded protein interacts with estrogen receptors and the heat shock proteins, Hsp70 and Hsp90. An homologous protein in rat has been shown to function in neuronal migration in the developing neocortex. A chromosomal translocation involving this gene is associated with a susceptibility to developmental dyslexia. Mutations in this gene are associated with deficits in reading and spelling. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream cell cycle progression 1 (CCPG1) gene.
Gene ID
161582
Gene Name (Vector)
dyslexia susceptibility 1 candidate 1
Gene Symbol
DYX1C1
HGNC ID
HGNC:21493
ORF Size (aa)
1146
ORF Size (bp)
1146 bp
RefSeq ID
NM_130810
RefSeq Synonyms
NM_130810, NM_001033560, NM_001033559, BC062564,
Species
human
UniGene ID
Hs.126403

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.