human HEPACAM shRNA silencing AAV

Name
AAV-h-HEPACAM-shRNA

Cat No
shAAV-232228

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human HEPACAM.

shAAV-232228

AAV-h-HEPACAM-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HEPACAM (hepatic and glial cell adhesion molecule). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

GlialCAM; MLC2A; MLC2B

Description (Vector)

HEPACAM is a single-pass type I membrane protein that localizes to the cytoplasmic side of the cell membrane. The encoded protein acts as a homodimer and is involved in cell motility and cell-matrix interactions. The expression of this gene is downregulated or undetectable in many cancer cell lines, so this may be a tumor suppressor gene.

Gene ID

220296

Gene Name (Vector)

hepatic and glial cell adhesion molecule

Gene Symbol

HEPACAM

HGNC ID

HGNC:26361

ORF Size (aa)

1251

ORF Size (bp)

1251 bp

RefSeq ID

NM_152722

RefSeq Synonyms

NM_152722, BC113562, BC104831,

Species

human

UniGene ID

Hs.719285

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.