human FAM38A shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PIEZO1.
shAAV-231912
AAV-h-FAM38A-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PIEZO1 (piezo type mechanosensitive ion channel component 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DHS; FAM38A; LMPH3; Mib
Description (Vector)
Piezos are large transmembrane proteins conserved among various species, all having between 24 and 36 predicted transmembrane domains. 'Piezo' comes from the Greek 'piesi,' meaning 'pressure.' The FAM38A gene encodes PIEZO1, a protein that induces mechanically activated (MA) currents in various cell types (Coste et al., 2010 (PubMed 20813920)).(supplied by OMIM, Nov 2010)
Gene ID
9780
Gene Name (Vector)
piezo type mechanosensitive ion channel component 1
Gene Symbol
PIEZO1
HGNC ID
HGNC:28993
ORF Size (aa)
6108
ORF Size (bp)
6108 bp
RefSeq ID
NM_001142864
RefSeq Synonyms
NM_001142864, BC150271, BC008073,
Species
human
UniGene ID
Hs.513807
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.