human ITGA1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ITGA1.
shAAV-231674
AAV-h-ITGA1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ITGA1 (integrin subunit alpha 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD49a; VLA1
Description (Vector)
ITGA1 encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding.
Gene ID
3672
Gene Name (Vector)
integrin subunit alpha 1
Gene Symbol
ITGA1
HGNC ID
HGNC:6134
ORF Size (aa)
3540
ORF Size (bp)
3540 bp
RefSeq ID
NM_181501
RefSeq Synonyms
NM_181501, BC137122, BC137121,
Species
human
UniGene ID
Hs.
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.