human EPB41 shRNA silencing AAV

Name
AAV-h-EPB41-shRNA

Cat No
shAAV-231295

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human EPB41.

shAAV-231295

AAV-h-EPB41-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human EPB41 (erythrocyte membrane protein band 4.1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

4.1R; EL1; HE

Description (Vector)

EPB41, together with spectrin and actin, constitute the red cell membrane cytoskeletal network. This complex plays a critical role in erythrocyte shape and deformability. Mutations in this gene are associated with type 1 elliptocytosis (EL1). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene ID

2035

Gene Name (Vector)

erythrocyte membrane protein band 4.1

Gene Symbol

EPB41

HGNC ID

HGNC:3377

ORF Size (aa)

2163

ORF Size (bp)

2163 bp

RefSeq ID

NM_004437

RefSeq Synonyms

NM_203343, NM_203342, NM_004437, NM_001166007, NM_001166006, NM_001166005, BC096105, BC039079,

Species

human

UniGene ID

Hs.175437

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.