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human RNASE4 shRNA silencing AAV

Name 
AAV-h-RNASE4-shRNA
Cat No 
shAAV-230977
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human RNASE4.

shAAV-230977
AAV-h-RNASE4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RNASE4 (ribonuclease A family member 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
RAB1; RNS4
Description (Vector)
RNASE4 belongs to the pancreatic ribonuclease family. It plays an important role in mRNA cleavage and has marked specificity towards the 3' side of uridine nucleotides. Alternative splicing results in two transcript variants encoding the same protein. This gene and the gene that encodes angiogenin share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region.
Gene ID
6038
Gene Name (Vector)
ribonuclease A family member 4
Gene Symbol
RNASE4
HGNC ID
HGNC:10047
ORF Size (aa)
444
RefSeq ID
NM_002937
RefSeq Synonyms
NM_194431, NM_002937, NM_001282193, NM_001282192, BC015520,
Species
human
UniGene ID
Hs.

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.