human LEPROT shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human LEPROT.
shAAV-230679
AAV-h-LEPROT-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human LEPROT (leptin receptor overlapping transcript). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
LEPR; OB-RGRP; OBRGRP; VPS55
Description (Vector)
LEPROT is associated with the Golgi complex and endosomes and has a role in cell surface expression of growth hormone receptor (GHR; MIM 600946) and leptin receptor (OBR, or LEPR; MIM 601007), thereby altering receptor-mediated cell signaling (Couturier et al., 2007 (PubMed 18042720); Touvier et al., 2009 (PubMed 19907080)).(supplied by OMIM, Jul 2010)
Gene ID
54741
Gene Name (Vector)
leptin receptor overlapping transcript
Gene Symbol
LEPROT
HGNC ID
HGNC:29477
ORF Size (aa)
396
RefSeq ID
NM_017526
RefSeq Synonyms
NM_017526, NM_001198683, NM_001198681, BC056250,
Species
human
UniGene ID
Hs.
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.