human CDKL3 shRNA silencing AAV

Name
AAV-h-CDKL3-shRNA

Cat No
shAAV-230170

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human CDKL3.

shAAV-230170

AAV-h-CDKL3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CDKL3 (cyclin dependent kinase like 3). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

NKIAMRE

Description (Vector)

CDKL3 is a member of cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This gene was identified as a gene absent in leukemic patients with chromosome 5q deletion. This loss may be an important determinant of dysmyelopoiesis. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene ID

51265

Gene Name (Vector)

cyclin dependent kinase like 3

Gene Symbol

CDKL3

HGNC ID

HGNC:15483

ORF Size (aa)

1779

ORF Size (bp)

1779 bp

RefSeq ID

NM_016508

RefSeq Synonyms

NM_016508, NM_001300853, NM_001113575, BC041799,

Species

human

UniGene ID

Hs.

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.