human POLR2J3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human POLR2J3.
shAAV-230022
AAV-h-POLR2J3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human POLR2J3 (RNA polymerase II subunit J3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
POLR2J2; RPB11b1; RPB11b2
Description (Vector)
POLR2J3 is a member of the RNA polymerase II subunit 11 gene family, which includes three genes in a cluster on chromosome 7q22.1 and a pseudogene on chromosome 7p13. The founding member of this family, DNA directed RNA polymerase II polypeptide J, has been shown to encode a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This locus produces multiple, alternatively spliced transcripts that potentially express isoforms with distinct C-termini compared to DNA directed RNA polymerase II polypeptide J. Most or all variants are spliced to include additional non-coding exons at the 3' end which makes them candidates for nonsense-mediated decay (NMD). Consequently, it is not known if this locus expresses a protein or proteins in vivo.
Gene ID
548644
Gene Name (Vector)
RNA polymerase II subunit J3
Gene Symbol
POLR2J3
ORF Size (aa)
348
RefSeq ID
NM_001097615
RefSeq Synonyms
NM_001097615, BC156863,
Species
human
UniGene ID
Hs.
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.