human EPB49 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human DMTN.
shAAV-229697
AAV-h-EPB49-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human DMTN (dematin actin binding protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DMT; EPB49
Description (Vector)
Dematin, or EPB49, is an actin-bundling protein originally identified in the erythroid membrane skeleton. Its actin-bundling activity is abolished upon phosphorylation by cAMP-dependent protein kinase and is restored after dephosphorylation (Rana et al., 1993 (PubMed 8341682)).(supplied by OMIM, Apr 2009)
Gene ID
2039
Gene Name (Vector)
dematin actin binding protein
Gene Symbol
DMTN
HGNC ID
HGNC:3382
ORF Size (aa)
1218
ORF Size (bp)
1218 bp
RefSeq ID
NM_001978
RefSeq Synonyms
NM_001978, NM_001323401, NM_001323400, NM_001323399, NM_001323398, NM_001323397, NM_001323396, NM_001323395, NM_001323394, NM_001323393, NM_001323392, NM_001323391, NM_001323390, NM_001323389, NM_001323388, NM_001323387, NM_001323385, NM_001323384, NM_001323383, NM_001323382, NM_001323381, NM_001323380, NM_001323379, NM_001323378, NM_001302817, NM_001302816, NM_001114139, NM_001114138, NM_001114137, NM_001114136, NM_001114135, BC052805, BC017445, BC006318,
Species
human
UniGene ID
Hs.106124
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.