human PDE7A shRNA silencing AAV

Name
AAV-h-PDE7A-shRNA

Cat No
shAAV-229335

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human PDE7A.

shAAV-229335

AAV-h-PDE7A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PDE7A (phosphodiesterase 7A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HCP1; PDE7

Description (Vector)

PDE7A belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE7 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene ID

5150

Gene Name (Vector)

phosphodiesterase 7A

Gene Symbol

PDE7A

HGNC ID

HGNC:8791

ORF Size (aa)

1371

ORF Size (bp)

1371 bp

RefSeq ID

NM_002603

RefSeq Synonyms

NM_002603, NM_001242318, BC126360,

Species

human

UniGene ID

Hs.527119

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.