human UBXN6 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human UBXN6.
shAAV-229142
AAV-h-UBXN6-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human UBXN6 (UBX domain protein 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CTB-50L17.16; UBX domain containing 1; UBX domain-containing 2; UBX domain-containing protein 1; UBX domain-containing protein 6; UBXD1; UBXDC2
Description (eCommerce)
UBX-domain-containing protein 1 (UBXD1) acts in a complex with VCP and cooperates with USP7 in promoting MDM2 deubiquitination and stabilization. MDM2 stabilization leads to MDM2-dependent TP53 degradation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9BZV1].
Gene ID
80700
Gene Name (eCommerce)
UBX domain protein 6
Gene Name (Vector)
UBX domain protein 6
Gene Symbol
UBXN6
HGNC ID
HGNC:14928
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1167
ORF Size (bp)
1167 bp
Protein Name (eCommerce)
UBX domain-containing protein 6
RefSeq ID
NM_025241
RefSeq Synonyms
NM_025241, NM_001171091, BC008288,
Research Areas
Cytoskeleton,Ubiquitination
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
UBX-domain-containing protein 1 (UBXD1) acts in a complex with VCP and cooperates with USP7 in promoting MDM2 deubiquitination and stabilization. MDM2 stabilization leads to MDM2-dependent TP53 degradation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9BZV1].
UniGene ID
Hs.435255
UniProt ID (eCommerce)
Q9BZV1
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.