human IL23A shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human IL23A.
shAAV-229103
AAV-h-IL23A-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human IL23A (interleukin 23 subunit alpha). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
IL-23; IL-23A; IL23P19; P19; SGRF
Description (Vector)
IL23A encodes a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B). The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit, IL23R. Both IL23 and IL12 can activate the transcription activator STAT4, and stimulate the production of interferon-gamma (IFNG). In contrast to IL12, which acts mainly on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells.
Gene ID
51561
Gene Name (Vector)
interleukin 23 subunit alpha
Gene Symbol
IL23A
HGNC ID
HGNC:15488
ORF Size (aa)
570
RefSeq ID
NM_016584
RefSeq Synonyms
NM_016584, BC067513, BC067512, BC067511, BC066269, BC066268, BC066267,
Species
human
UniGene ID
Hs.98309
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.