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human CHRM5 shRNA silencing AAV

Name 
AAV-h-CHRM5-shRNA
Cat No 
shAAV-229051
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CHRM5.

shAAV-229051
AAV-h-CHRM5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CHRM5 (cholinergic receptor muscarinic 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HM5
Description (Vector)
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, stimulation of this receptor is known to increase cyclic AMP levels.
Gene ID
1133
Gene Name (Vector)
cholinergic receptor muscarinic 5
Gene Symbol
CHRM5
HGNC ID
HGNC:1954
ORF Size (aa)
1599
ORF Size (bp)
1599 bp
RefSeq ID
NM_012125
RefSeq Synonyms
NM_012125, NM_001320917, BC068528, BC041805,
Species
human
UniGene ID
Hs.584747

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.