human ZNF451 shRNA silencing AAV

Name
AAV-h-ZNF451-shRNA

Cat No
shAAV-228582

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human ZNF451.

shAAV-228582

AAV-h-ZNF451-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ZNF451 (zinc finger protein 451). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

80

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

coactivator for steroid receptors; COASTER; dJ417I1.1; E3 SUMO-protein ligase ZNF451; E3 SUMO-protein transferase ZNF451; Zinc finger protein 451

Description (eCommerce)

Zinc finger protein 451, whose UniProt recommended name is UE3 SUMO-protein ligase ZNF451, plays a role in protein SUMO2 modification in response to stress caused by DNA damage [taken from UniProtKB (Entry: Q9Y4E5)].

Gene ID

26036

Gene Name (eCommerce)

zinc finger protein 451

Gene Name (Vector)

zinc finger protein 451

Gene Symbol

ZNF451

HGNC ID

HGNC:21091

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

2799

ORF Size (bp)

2799 bp

Protein Name (eCommerce)

E3 SUMO-protein ligase ZNF451

RefSeq ID

NM_015555

RefSeq Synonyms

NM_015555, NM_001257273, NM_001031623, BC098382, BC021712,

Research Areas

Transcription Factor/Regulator,Zinc-finger

Research Areas (Faceted)

cell_biology,transcription_translation

Species

human

Target Sentence

Zinc finger protein 451, whose UniProt recommended name is UE3 SUMO-protein ligase ZNF451, plays a role in protein SUMO2 modification in response to stress caused by DNA damage [taken from UniProtKB (Entry: Q9Y4E5)].

UniGene ID

Hs.705485

UniProt ID (eCommerce)

Q9Y4E5

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.