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human ZNF189 shRNA silencing AAV

Name 
AAV-h-ZNF189-shRNA
Cat No 
shAAV-228359
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ZNF189.

shAAV-228359
AAV-h-ZNF189-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ZNF189 (zinc finger protein 189). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
50
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
Kruppel-like zinc finger proteins such as ZNF189 contain a conserved stretch of 7 amino acids that connects a variable number of DNA-binding zinc finger repeats of the cys(2)his(2) (C2H2) type (summarized by Odeberg et al., 1998 (PubMed 9653648)). Approximately 30% of human Kruppel-like zinc finger proteins contain an N-terminal Kruppel-associated box (KRAB) domain. The KRAB domain consists of approximately 75 amino acids that may be subdivided into an A box, which is present in every KRAB domain and is essential for transcriptional repression, and a B box, which is not always present.(supplied by OMIM, May 2010)
Gene ID
7743
Gene Name (Vector)
zinc finger protein 189
Gene Symbol
ZNF189
HGNC ID
HGNC:12980
ORF Size (aa)
1836
ORF Size (bp)
1836 bp
RefSeq ID
NM_003452
RefSeq Synonyms
NM_197977, NM_003452, NM_001278240, NM_001278232, NM_001278231, BC143877, BC143876, BC126120, BC092425,
Species
human
UniGene ID
Hs.50123

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.