human ZIC3 shRNA silencing AAV

Name 
AAV-h-ZIC3-shRNA
Cat No 
shAAV-228256
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ZIC3.

shAAV-228256
AAV-h-ZIC3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ZIC3 (Zic family member 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HTX; HTX1; VACTERLX; ZNF203
Description (Vector)
ZIC3 encodes a member of the ZIC family of C2H2-type zinc finger proteins. This nuclear protein probably functions as a transcription factor in early stages of left-right body axis formation. Mutations in this gene cause X-linked visceral heterotaxy, which includes congenital heart disease and left-right axis defects in organs.
Gene ID
7547
Gene Name (Vector)
Zic family member 3
Gene Symbol
ZIC3
HGNC ID
HGNC:12874
ORF Size (aa)
1401
ORF Size (bp)
1401 bp
RefSeq ID
NM_003413
RefSeq Synonyms
NM_003413, NM_001330661, BC113395, BC113393, BC111854,
Species
human
UniGene ID
Hs.111227

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.