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human ZHX1 shRNA silencing AAV

Name 
AAV-h-ZHX1-shRNA
Cat No 
shAAV-228248
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ZHX1.

shAAV-228248
AAV-h-ZHX1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ZHX1 (zinc fingers and homeoboxes 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
zinc finger and homeodomain protein 1; zinc fingers and homeobox 1; zinc fingers and homeoboxes protein 1
Description (eCommerce)
Zinc-fingers and homeoboxes protein 1 (ZHX1) is part of a gene family of transcriptional repressors that interacts with the nuclear factor Y (NF-Y) or CCAAT-binding protein (CBF) heterotrimeric transcription factor. ZHX1 contains two zinc-fingers and five homeodomain motifs. ZHX1 can form homodimers or heterodimers with ZHX2 and ZHX3.
Description (Vector)
The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 1 of this gene family. In addition to forming homodimers, this protein heterodimerizes with members 2 and 3 of the zinc fingers and homeoboxes family. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream chromosome 8 open reading frame 76 (C8orf76) gene.
Gene ID
11244
Gene Name (eCommerce)
zinc fingers and homeoboxes 1
Gene Name (Vector)
zinc fingers and homeoboxes 1
Gene Symbol
ZHX1
HGNC ID
HGNC:12871
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2622
ORF Size (bp)
2622 bp
Protein Name (eCommerce)
Zinc fingers and homeoboxes protein 1
RefSeq ID
NM_007222
RefSeq Synonyms
NM_007222, NM_001017926, BC040481,
Research Areas
Transcription Factor/Regulator,Zinc-finger
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
Zinc-fingers and homeoboxes protein 1 (ZHX1) is part of a gene family of transcriptional repressors that interacts with the nuclear factor Y (NF-Y) or CCAAT-binding protein (CBF) heterotrimeric transcription factor. ZHX1 contains two zinc-fingers and five homeodomain motifs. ZHX1 can form homodimers or heterodimers with ZHX2 and ZHX3.
UniGene ID
Hs.612084
UniProt ID (eCommerce)
Q9UKY1

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.