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human ZBTB7A shRNA silencing AAV

Name 
AAV-h-ZBTB7A-shRNA
Cat No 
shAAV-228082
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ZBTB7A.

shAAV-228082
AAV-h-ZBTB7A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ZBTB7A (zinc finger and BTB domain containing 7A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
factor binding IST protein 1; factor that binds to inducer of short transcripts protein 1; FBI1; FBI-1; HIV-1 1st-binding protein 1; HIV-1 inducer of short transcripts binding protein; leukemia/lymphoma-related factor; LRF; lymphoma related factor; POK erythroid myeloid ontogenic factor; pokemon; Pokemon 1; POZ and Krueppel erythroid myeloid ontogenic factor; TIP21; TTF-I-interacting peptide 21; ZBTB7; zinc finger and BTB domain containing 7A, HIV-1 inducer of short transcripts binding protein; zinc finger and BTB domain-containing protein 7A; zinc finger protein 857A; ZNF857A
Description (eCommerce)
Zinc-finger and BTB domain-containing protein 7A (ZBTB7A) binds IST (inducer of short transcript) DNA elements in the HIV promoter to facilitate short transcript synthesis. ZBTB7A identified as LRF also interacts with the LAZ-3/BCL-6 oncoprotein. Because ZBTB7A also contains a POZ domain it may serve a function in chromatin remodeling.
Gene ID
51341
Gene Name (eCommerce)
zinc finger and BTB domain containing 7A
Gene Name (Vector)
zinc finger and BTB domain containing 7A
Gene Symbol
ZBTB7A
HGNC ID
HGNC:18078
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1755
ORF Size (bp)
1755 bp
Protein Name (eCommerce)
Zinc finger and BTB domain-containing protein 7A
RefSeq ID
NM_015898
RefSeq Synonyms
NM_015898, NM_001317990, BC113511, BC084568,
Research Areas
Histone Modification,Immunology,Transcription Factor/Regulator,Zinc-finger
Research Areas (Faceted)
cell_biology,immunology,transcription_translation
Species
human
Target Sentence
Zinc-finger and BTB domain-containing protein 7A (ZBTB7A) binds IST (inducer of short transcript) DNA elements in the HIV promoter to facilitate short transcript synthesis. ZBTB7A identified as LRF also interacts with the LAZ-3/BCL-6 oncoprotein. Because ZBTB7A also contains a POZ domain it may serve a function in chromatin remodeling.
UniGene ID
Hs.591384
UniProt ID (eCommerce)
O95365

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.