human YWHAH shRNA silencing AAV

Name 
AAV-h-YWHAH-shRNA
Cat No 
shAAV-228005
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human YWHAH.

shAAV-228005
AAV-h-YWHAH-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human YWHAH (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
YWHA1
Description (Vector)
YWHAH product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. YWHAH contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder.
Gene ID
7533
Gene Name (Vector)
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
Gene Symbol
YWHAH
HGNC ID
HGNC:12853
ORF Size (aa)
741
RefSeq ID
NM_003405
RefSeq Synonyms
NM_003405, BC003047,
Species
human
UniGene ID
Hs.226755

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.