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human YARS2 shRNA silencing AAV

Name 
AAV-h-YARS2-shRNA
Cat No 
shAAV-227949
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human YARS2.

shAAV-227949
AAV-h-YARS2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human YARS2 (tyrosyl-tRNA synthetase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CGI-04; MLASA2; MT-TYRRS; TYRRS
Description (Vector)
YARS2 encodes a mitochondrial protein that catalyzes the attachment of tyrosine to tRNA(Tyr). Mutations in this gene are associated with myopathy with lactic acidosis and sideroblastic anemia type 2 (MLASA2).
Gene ID
51067
Gene Name (Vector)
tyrosyl-tRNA synthetase 2
Gene Symbol
YARS2
HGNC ID
HGNC:24249
ORF Size (aa)
1434
ORF Size (bp)
1434 bp
RefSeq ID
NM_001040436
RefSeq Synonyms
NM_001040436, BC015625,
Species
human
UniGene ID
Hs.505231

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.