human XK shRNA silencing AAV

Name 
AAV-h-XK-shRNA
Cat No 
shAAV-227885
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human XK.

shAAV-227885
AAV-h-XK-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human XK (X-linked Kx blood group). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
KX; NA; NAC; X1k; XKR1
Description (Vector)
This locus controls the synthesis of the Kell blood group 'precursor substance' (Kx). Mutations in this gene have been associated with McLeod syndrome, an X-linked, recessive disorder characterized by abnormalities in the neuromuscular and hematopoietic systems. The encoded protein has structural characteristics of prokaryotic and eukaryotic membrane transport proteins.
Gene ID
7504
Gene Name (Vector)
X-linked Kx blood group
Gene Symbol
XK
HGNC ID
HGNC:12811
ORF Size (aa)
1335
ORF Size (bp)
1335 bp
RefSeq ID
NM_021083
RefSeq Synonyms
NM_021083, BC036019,
Species
human
UniGene ID
Hs.78919

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.