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human WNT10B shRNA silencing AAV

Name 
AAV-h-WNT10B-shRNA
Cat No 
shAAV-227813
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human WNT10B.

shAAV-227813
AAV-h-WNT10B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human WNT10B (Wnt family member 10B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
SHFM6; STHAG8; WNT-12
Description (Vector)
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It may be involved in breast cancer, and its protein signaling is likely a molecular switch that governs adipogenesis. This protein is 96% identical to the mouse Wnt10b protein at the amino acid level. This gene is clustered with another family member, WNT1, in the chromosome 12q13 region.
Gene ID
7480
Gene Name (Vector)
Wnt family member 10B
Gene Symbol
WNT10B
HGNC ID
HGNC:12775
ORF Size (aa)
1170
RefSeq ID
NM_003394
RefSeq Synonyms
NM_003394, BC096356, BC096354, BC096353,
Species
human
UniGene ID
Hs.91985

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.