human WIPI1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human WIPI1.
shAAV-227793
AAV-h-WIPI1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human WIPI1 (WD repeat domain, phosphoinositide interacting 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ATG18; ATG18A; WIPI49
Description (Vector)
WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI1, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 (PubMed 15602573)).(supplied by OMIM, Mar 2008)
Gene ID
55062
Gene Name (Vector)
WD repeat domain, phosphoinositide interacting 1
Gene Symbol
WIPI1
HGNC ID
HGNC:25471
ORF Size (aa)
1341
ORF Size (bp)
1341 bp
RefSeq ID
NM_017983
RefSeq Synonyms
NM_017983, NM_001320772, BC039867,
Species
human
UniGene ID
Hs.463964
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.