human WIPI1 shRNA silencing AAV

Cat. No: shAAV-227793

Availability: 4-5 weeks

Name: AAV-h-WIPI1-shRNA

This is an AAV expressing shRNA for silencing of Human WIPI1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: WIPI1
Gene Name: WD repeat domain, phosphoinositide interacting 1
Gene ID: 55062
Gene Synonyms: ATG18; ATG18A; WIPI49
ORF Size: 1341 bp
RefSeq#: NM_017983
Gene Description: WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI1, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 (PubMed 15602573)).(supplied by OMIM, Mar 2008)
UniGene ID: Hs.463964
HGNC ID: HGNC:25471