human WFDC5 shRNA silencing AAV

Name
AAV-h-WFDC5-shRNA

Cat No
shAAV-227768

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human WFDC5.

shAAV-227768

AAV-h-WFDC5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human WFDC5 (WAP four-disulfide core domain 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

dJ211D12.5; PRG5; WAP1

Description (Vector)

WFDC5 encodes a member of the WAP-type four-disulfide core (WFDC) domain family. Most WFDC proteins contain only one WFDC domain, and this encoded protein contains two WFDC domains. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. WFDC5 belongs to the centromeric cluster.

Gene ID

149708

Gene Name (Vector)

WAP four-disulfide core domain 5

Gene Symbol

WFDC5

HGNC ID

HGNC:20477

ORF Size (aa)

372

RefSeq ID

NM_145652

RefSeq Synonyms

NM_145652, BC039173,

Species

human

UniGene ID

Hs.375031

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.