human WDR40A shRNA silencing AAV

Name
AAV-h-WDR40A-shRNA

Cat No
shAAV-227673

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human DCAF12.

shAAV-227673

AAV-h-WDR40A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DCAF12 (DDB1 and CUL4 associated factor 12). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CT102; KIAA1892; TCC52; WDR40A

Description (Vector)

DCAF12 encodes a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates.

Gene ID

25853

Gene Name (Vector)

DDB1 and CUL4 associated factor 12

Gene Symbol

DCAF12

HGNC ID

HGNC:19911

ORF Size (aa)

1362

ORF Size (bp)

1362 bp

RefSeq ID

NM_015397

RefSeq Synonyms

NM_015397, BC063823,

Species

human

UniGene ID

Hs.716472

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.