human VSNL1 shRNA silencing AAV

Name 
AAV-h-VSNL1-shRNA
Cat No 
shAAV-227563
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human VSNL1.

shAAV-227563
AAV-h-VSNL1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human VSNL1 (visinin like 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HLP3; HPCAL3; HUVISL1; VILIP; VILIP-1
Description (Vector)
VSNL1 is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.
Gene ID
7447
Gene Name (Vector)
visinin like 1
Gene Symbol
VSNL1
HGNC ID
HGNC:12722
ORF Size (aa)
576
RefSeq ID
NM_003385
RefSeq Synonyms
NM_003385, BC022012,
Species
human
UniGene ID
Hs.444212

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.