human VSIG4 shRNA silencing AAV

Name 
AAV-h-VSIG4-shRNA
Cat No 
shAAV-227562
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human VSIG4.

shAAV-227562
AAV-h-VSIG4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human VSIG4 (V-set and immunoglobulin domain containing 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CRIg; Z39IG
Description (Vector)
VSIG4 encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants.
Gene ID
11326
Gene Name (Vector)
V-set and immunoglobulin domain containing 4
Gene Symbol
VSIG4
HGNC ID
HGNC:17032
ORF Size (aa)
1200
RefSeq ID
NM_007268
RefSeq Synonyms
NM_007268, NM_001257403, NM_001184831, NM_001184830, NM_001100431, BC010525,
Species
human
UniGene ID
Hs.8904

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.