human VPS52 shRNA silencing AAV

Name
AAV-h-VPS52-shRNA

Cat No
shAAV-227546

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human VPS52.

shAAV-227546

AAV-h-VPS52-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human VPS52 (VPS52, GARP complex subunit). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ARE1; dJ1033B10.5; SAC2; SACM2L

Description (Vector)

VPS52 encodes a protein that is similar to the yeast suppressor of actin mutations 2 gene. The yeast protein forms a subunit of the tetrameric Golgi-associated retrograde protein complex that is involved in vesicle trafficking from from both early and late endosomes, back to the trans-Golgi network. VPS52 is located on chromosome 6 in a head-to-head orientation with the gene encoding ribosomal protein S18.

Gene ID

6293

Gene Name (Vector)

VPS52, GARP complex subunit

Gene Symbol

VPS52

HGNC ID

HGNC:10518

ORF Size (aa)

2172

ORF Size (bp)

2172 bp

RefSeq ID

NM_022553

RefSeq Synonyms

NM_022553, NM_001289176, NM_001289175, NM_001289174, BC040114, BC032108,

Species

human

UniGene ID

Hs.480356

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.