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human VPS37C shRNA silencing AAV

Name 
AAV-h-VPS37C-shRNA
Cat No 
shAAV-227536
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human VPS37C.

shAAV-227536
AAV-h-VPS37C-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human VPS37C (VPS37C, ESCRT-I subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
VPS37C is a subunit of ESCRT-I (endosomal sorting complex required for transport I), a complex in the class E vacuolar protein sorting (VPS) pathway required for sorting ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies (Eastman et al., 2005 (PubMed 15509564)).(supplied by OMIM, Mar 2008)
Gene ID
55048
Gene Name (Vector)
VPS37C, ESCRT-I subunit
Gene Symbol
VPS37C
HGNC ID
HGNC:26097
ORF Size (aa)
1068
RefSeq ID
NM_017966
RefSeq Synonyms
NM_017966, BC142702, BC141827,
Species
human
UniGene ID
Hs.523715

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.