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human VEZT shRNA silencing AAV

Name 
AAV-h-VEZT-shRNA
Cat No 
shAAV-227464
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human VEZT.

shAAV-227464
AAV-h-VEZT-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human VEZT (vezatin, adherens junctions transmembrane protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
VEZATIN
Description (Vector)
VEZT encodes a transmembrane protein which has been localized to adherens junctions and shown to bind to myosin VIIA. Examination of expression of this gene in gastric cancer tissues have shown that expression is decreased which appears to be related to hypermethylation of the promoter. Expression of this gene may also be inhibited by binding of a specific microRNA to a target sequence in the 3' UTR of the transcripts. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants.
Gene ID
55591
Gene Name (Vector)
vezatin, adherens junctions transmembrane protein
Gene Symbol
VEZT
ORF Size (aa)
2196
ORF Size (bp)
2196 bp
RefSeq ID
NM_017599
RefSeq Synonyms
NM_017599, BC064939,
Species
human
UniGene ID
Hs.24135

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.