human UTP6 shRNA silencing AAV

Name
AAV-h-UTP6-shRNA

Cat No
shAAV-227367

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human UTP6.

shAAV-227367

AAV-h-UTP6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human UTP6 (UTP6, small subunit processome component). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

80

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

C17orf40; HCA66; hepatocellular carcinoma-associated antigen 66; multiple hat domains protein; U3 small nucleolar RNA-associated protein 6 homolog; UTP6, small subunit (SSU) processome component, homolog

Description (eCommerce)

HCA66 (hepatocellular carcinoma-associated antigen 66) is also known as UTP6 and is a subunit of the UtpB subcomplex which is part of the SSU (small subunit) processome. HCA66 contains a HAT (half-a-tetracopeptide repeat) domain which is found only in proteins involved in RNA metabolism. HCA66 has also been identified as a component of the centrosome and as a regulator of gamma-tubulin.

Gene ID

55813

Gene Name (eCommerce)

UTP6, small subunit processome component

Gene Name (Vector)

UTP6, small subunit processome component

Gene Symbol

UTP6

HGNC ID

HGNC:18279

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1794

ORF Size (bp)

1794 bp

Protein Name (eCommerce)

U3 small nucleolar RNA-associated protein 6 homolog

RefSeq ID

NM_018428

RefSeq Synonyms

NM_018428, BC035325,

Research Areas

RNA Processing

Research Areas (Faceted)

cell_biology,genetics,transcription_translation

Species

human

Target Sentence

HCA66 (hepatocellular carcinoma-associated antigen 66) is also known as UTP6 and is a subunit of the UtpB subcomplex which is part of the SSU (small subunit) processome. HCA66 contains a HAT (half-a-tetracopeptide repeat) domain which is found only in proteins involved in RNA metabolism. HCA66 has also been identified as a component of the centrosome and as a regulator of gamma-tubulin.

UniGene ID

Hs.589862

UniProt ID (eCommerce)

Q9NYH9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.