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human USP9X shRNA silencing AAV

Name 
AAV-h-USP9X-shRNA
Cat No 
shAAV-227348
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human USP9X.

shAAV-227348
AAV-h-USP9X-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human USP9X (ubiquitin specific peptidase 9, X-linked). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
85
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
deubiquitinating enzyme FAF-X; DFFRX; Drosophila fat facets related, X-linked; FAF; FAM; fat facets in mammals; fat facets protein related, X-linked; Fat facets protein-related, X-linked; hFAM; MRX99; MRXS99F; probable ubiquitin carboxyl-terminal hydrolase FAF-X; ubiquitin specific protease 9, X chromosome (fat facets-like Drosophila); ubiquitin thioesterase FAF-X; ubiquitin thiolesterase FAF-X; ubiquitin-specific processing protease FAF-X; ubiquitin-specific protease 9, X chromosome; Ubiquitin-specific-processing protease FAF-X
Description (eCommerce)
USP9X is an ubiquitin-specific protease involved in the removal and recycling of ubiquitin from proteins degraded in proteasomes. USP9X is located on the X-chromosome but escapes X-inactivation. Defects in USP9X may cause gonadal degeneration in Turner syndrome.
Description (Vector)
USP9X is a member of the peptidase C19 family and encodes a protein that is similar to ubiquitin-specific proteases. Though this gene is located on the X chromosome, it escapes X-inactivation. Mutations in this gene have been associated with Turner syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene ID
8239
Gene Name (eCommerce)
ubiquitin specific peptidase 9 X-linked
Gene Name (Vector)
ubiquitin specific peptidase 9, X-linked
Gene Symbol
USP9X
HGNC ID
HGNC:12632
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
7665
ORF Size (bp)
7665 bp
Protein Name (eCommerce)
Probable ubiquitin carboxyl-terminal hydrolase FAF-X
RefSeq ID
NM_001039591
RefSeq Synonyms
NM_001039591, NM_001039590, BC172429,
Research Areas
Cell Cycle,Cell Division,Gene Expression,Signal Transduction,TGF-beta Signaling,Transcription Factor/Regulator,Ubiquitination
Research Areas (Faceted)
signal_transduction,cell_biology,cell_cycle,genetics,transcription_translation,signal_transduction,immunology,genetics,transcription_translation
Species
human
Target Sentence
USP9X is an ubiquitin-specific protease involved in the removal and recycling of ubiquitin from proteins degraded in proteasomes. USP9X is located on the X-chromosome but escapes X-inactivation. Defects in USP9X may cause gonadal degeneration in Turner syndrome.
UniGene ID
Hs.77578
UniProt ID (eCommerce)
Q93008

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.