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human USH1G shRNA silencing AAV

Name 
AAV-h-USH1G-shRNA
Cat No 
shAAV-227272
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human USH1G.

shAAV-227272
AAV-h-USH1G-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human USH1G (USH1 protein network component sans). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ANKS4A; SANS
Description (Vector)
USH1G encodes a protein that contains three ankyrin domains, a class I PDZ-binding motif and a sterile alpha motif. The encoded protein interacts with harmonin, which is associated with Usher syndrome type 1C. This protein plays a role in the development and maintenance of the auditory and visual systems and functions in the cohesion of hair bundles formed by inner ear sensory cells. Mutations in this gene are associated with Usher syndrome type 1G (USH1G).
Gene ID
124590
Gene Name (Vector)
USH1 protein network component sans
Gene Symbol
USH1G
HGNC ID
HGNC:16356
ORF Size (aa)
1386
ORF Size (bp)
1386 bp
RefSeq ID
NM_173477
RefSeq Synonyms
NM_173477, NM_001282489, BC101099, BC101098, BC101097, BC101096,
Species
human
UniGene ID
Hs.376688

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.