human USF2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human USF2.
shAAV-227270
AAV-h-USF2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human USF2 (upstream transcription factor 2, c-fos interacting). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
bHLHb12; c-fos interacting protein; class B basic helix-loop-helix protein 12; FIP; FOS-interacting protein; major late transcription factor 2; upstream stimulatory factor 2; Upstream transcription factor 2
Description (eCommerce)
Upstream stimulatory factor 2 (USF2) is a transcription factor that binds to a symmetrical DNA sequence (E-box) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15853].
Description (Vector)
USF2 encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. Two transcript variants encoding distinct isoforms have been identified for this gene.
Gene ID
7392
Gene Name (eCommerce)
upstream transcription factor 2, c-fos interacting
Gene Name (Vector)
upstream transcription factor 2, c-fos interacting
Gene Symbol
USF2
HGNC ID
HGNC:12594
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1041
Protein Name (eCommerce)
Upstream stimulatory factor 2
RefSeq ID
NM_003367
RefSeq Synonyms
NM_207291, NM_003367, NM_001321150, BC049821,
Research Areas
Host-Virus Interactions,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,infectious_disease,transcription_translation
Species
human
Target Sentence
Upstream stimulatory factor 2 (USF2) is a transcription factor that binds to a symmetrical DNA sequence (E-box) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15853].
UniGene ID
Hs.454534
UniProt ID (eCommerce)
Q15853
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.