human UROD shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human UROD.
shAAV-227265
AAV-h-UROD-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human UROD (uroporphyrinogen decarboxylase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PCT; UPD
Description (Vector)
UROD encodes an enzyme in the heme biosynthetic pathway. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are known to cause familial porphyria cutanea tarda and hepatoerythropoetic porphyria.
Gene ID
7389
Gene Name (Vector)
uroporphyrinogen decarboxylase
Gene Symbol
UROD
HGNC ID
HGNC:12591
ORF Size (aa)
1104
RefSeq ID
NM_000374
RefSeq Synonyms
NM_000374, BC001778,
Species
human
UniGene ID
Hs.78601
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.