human UPRT shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human UPRT.
shAAV-227239
AAV-h-UPRT-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human UPRT (uracil phosphoribosyltransferase homolog). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
FUR1; UPP
Description (Vector)
UPRT encodes uracil phosphoribosyltransferase, which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. The enzyme localizes to the nucleus and cytoplasm. The protein is a potential target for rational design of drugs to treat parasitic infections and cancer.
Gene ID
139596
Gene Name (Vector)
uracil phosphoribosyltransferase homolog
Gene Symbol
UPRT
HGNC ID
HGNC:28334
ORF Size (aa)
930
RefSeq ID
NM_145052
RefSeq Synonyms
NM_145052, NM_001307944, BC015116,
Species
human
UniGene ID
Hs.91612
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.