human UPK3B shRNA silencing AAV

Name
AAV-h-UPK3B-shRNA

Cat No
shAAV-227234

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human UPK3B.

shAAV-227234

AAV-h-UPK3B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human UPK3B (uroplakin 3B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

P35; UP3B; UPIIIB

Description (Vector)

UPK3B is a minor component of the apical plaques of mammalian urothelium that binds and dimerizes with uroplakin-1b (UPK1B; MIM 602380), one of the major conserved urothelium membrane proteins. The other major conserved integral membrane proteins of urothelial plaques are UPK1A (MIM 611557), UPK2 (MIM 611558), and UPK3A (MIM 611559) (Deng et al., 2002 (PubMed 12446744)).(supplied by OMIM, Mar 2008)

Gene ID

80761

Gene Name (Vector)

uroplakin 3B

Gene Symbol

UPK3B

HGNC ID

HGNC:21444

ORF Size (aa)

963

RefSeq ID

NM_182684

RefSeq Synonyms

NM_182684, NM_182683, NM_030570, BC004304,

Species

human

UniGene ID

Hs.488861

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.