human UNC5B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human UNC5B.
shAAV-227197
AAV-h-UNC5B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human UNC5B (unc-5 netrin receptor B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
p53RDL1; UNC5H2
Description (Vector)
UNC5B encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene.
Gene ID
219699
Gene Name (Vector)
unc-5 netrin receptor B
Gene Symbol
UNC5B
HGNC ID
HGNC:12568
ORF Size (aa)
2838
ORF Size (bp)
2838 bp
RefSeq ID
NM_170744
RefSeq Synonyms
NM_170744, NM_001244889, BC166694,
Species
human
UniGene ID
Hs.522997
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.