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human UNC13A shRNA silencing AAV

Name 
AAV-h-UNC13A-shRNA
Cat No 
shAAV-227181
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human UNC13A.

shAAV-227181
AAV-h-UNC13A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human UNC13A (unc-13 homolog A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Munc13-1
Description (Vector)
UNC13A encodes a member of the UNC13 family. UNC13 proteins bind to phorbol esters and diacylglycerol and play important roles in neurotransmitter release at synapses. Single nucleotide polymorphisms in this gene may be associated with sporadic amyotrophic lateral sclerosis.
Gene ID
23025
Gene Name (Vector)
unc-13 homolog A
Gene Symbol
UNC13A
HGNC ID
HGNC:23150
ORF Size (aa)
5373
ORF Size (bp)
5373 bp
RefSeq ID
NM_001080421
RefSeq Synonyms
NM_001080421, BC172223,
Species
human
UniGene ID
Hs.164502

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.