human UBR2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human UBR2.
shAAV-227079
AAV-h-UBR2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human UBR2 (ubiquitin protein ligase E3 component n-recognin 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
bA49A4.1; C6orf133; dJ242G1.1; dJ392M17.3; E3 ubiquitin-protein ligase UBR2; N-recognin-2; RING-type E3 ubiquitin transferase UBR2; ubiquitin-protein ligase E3-alpha-2; ubiquitin-protein ligase E3-alpha-II
Description (eCommerce)
UBR2 is an E3 ubiquitin ligase of the N-end rule proteolytic pathway that targets proteins with destabilizing N-terminal residues for polyubiquitylation and proteasome-mediated degradation [taken from NCBI Entrez Gene (Gene ID: 23304)].
Description (Vector)
UBR2 encodes an E3 ubiquitin ligase of the N-end rule proteolytic pathway that targets proteins with destabilizing N-terminal residues for polyubiquitylation and proteasome-mediated degradation. Alternative splicing results in multiple transcript variants.
Gene ID
23304
Gene Name (eCommerce)
ubiquitin protein ligase E3 component n-recognin 2
Gene Name (Vector)
ubiquitin protein ligase E3 component n-recognin 2
Gene Symbol
UBR2
HGNC ID
HGNC:21289
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
5265
ORF Size (bp)
5265 bp
Protein Name (eCommerce)
E3 ubiquitin-protein ligase UBR2
RefSeq ID
NM_015255
RefSeq Synonyms
NM_015255, NM_001184801, BC156045, BC064512,
Research Areas
Antigen Processing and Presentation,Cell Cycle,Histone Modification,Immunology,Meiosis,Spermatogenesis,Zinc-finger
Research Areas (Faceted)
cell_biology,cell_cycle,developmental_biology,genetics,immunology
Species
human
Target Sentence
UBR2 is an E3 ubiquitin ligase of the N-end rule proteolytic pathway that targets proteins with destabilizing N-terminal residues for polyubiquitylation and proteasome-mediated degradation [taken from NCBI Entrez Gene (Gene ID: 23304)].
UniGene ID
Hs.529925
UniProt ID (eCommerce)
Q8IWV8
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.