human UBN1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human UBN1.
shAAV-227068
AAV-h-UBN1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human UBN1 (ubinuclein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HIRA-binding protein; Protein VT4; ubinuclein-1; ubiquitously expressed nuclear protein; VT; VT4
Description (eCommerce)
Ubinuclein-1 acts as a novel regulator of senescence. It is involved in the formation of senescence-associated heterochromatin foci (SAHF), which repress expression of proliferation-promoting genes. Ubinuclein-1 binds to proliferation-promoting genes and may be required for replication-independent chromatin assembly.
Gene ID
29855
Gene Name (eCommerce)
ubinuclein 1
Gene Name (Vector)
ubinuclein 1
Gene Symbol
UBN1
HGNC ID
HGNC:12506
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3402
ORF Size (bp)
3402 bp
Protein Name (eCommerce)
Ubinuclein-1
RefSeq ID
NM_016936
RefSeq Synonyms
NM_016936, NM_001288656, NM_001079514, BC157077, BC156176,
Research Areas
Chromatin Remodeling,Host-Virus Interactions,Kinase/Phosphatase,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,genetics,infectious_disease,signal_transduction,transcription_translation
Species
human
Target Sentence
Ubinuclein-1 acts as a novel regulator of senescence. It is involved in the formation of senescence-associated heterochromatin foci (SAHF), which repress expression of proliferation-promoting genes. Ubinuclein-1 binds to proliferation-promoting genes and may be required for replication-independent chromatin assembly.
UniGene ID
Hs.440219
UniProt ID (eCommerce)
Q9NPG3
Recently Viewed Products
Ad-CMV-Luc
Cat No: 1000
Ad-CMV-Akt1 (Myr)
Cat No: 1020
Ad-CMV-Akt1 (dn)
Cat No: 1021
Ad-CMV-Akt1 (wt)
Cat No: 1022
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.