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human UBL5 shRNA silencing AAV

Name 
AAV-h-UBL5-shRNA
Cat No 
shAAV-227061
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human UBL5.

shAAV-227061
AAV-h-UBL5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human UBL5 (ubiquitin like 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HUB1
Description (Vector)
UBL5 encodes a member of a group of proteins similar to ubiquitin. The encoded protein is not thought to degrade proteins like ubiquitin but to affect their function through being bound to target proteins by an isopeptide bond. The gene product has been studied as a link to predisposition to obesity based on its expression in Psammomys obesus, the fat sand rat, which is an animal model for obesity studies. Variation in this gene was found to be significantly associated with some metabolic traits (PMID: 15331561) but not associated with childhood obesity (PMID: 19189687). Pseudogenes of this gene are located on chromsomes 3, 5 and 17. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Gene ID
59286
Gene Name (Vector)
ubiquitin like 5
Gene Symbol
UBL5
HGNC ID
HGNC:13736
ORF Size (aa)
222
RefSeq ID
NM_024292
RefSeq Synonyms
NM_024292, NM_001048241, BC110839, BC007053,
Species
human
UniGene ID
Hs.534477

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.