human UBE2R2 shRNA silencing AAV

Name
AAV-h-UBE2R2-shRNA

Cat No
shAAV-227030

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human UBE2R2.

shAAV-227030

AAV-h-UBE2R2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human UBE2R2 (ubiquitin conjugating enzyme E2 R2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CDC34B; E2-CDC34B; UBC3B

Description (Vector)

Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation.

Gene ID

54926

Gene Name (Vector)

ubiquitin conjugating enzyme E2 R2

Gene Symbol

UBE2R2

HGNC ID

HGNC:19907

ORF Size (aa)

717

RefSeq ID

NM_017811

RefSeq Synonyms

NM_017811, BC047584, BC004862,

Species

human

UniGene ID

Hs.718444

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.