human UBE2N shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human UBE2N.
shAAV-227025
AAV-h-UBE2N-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human UBE2N (ubiquitin conjugating enzyme E2 N). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HEL-S-71; UBC13; UbcH-ben; UbcH13; UBCHBEN
Description (Vector)
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Studies in mouse suggest that this protein plays a role in DNA postreplication repair.
Gene ID
7334
Gene Name (Vector)
ubiquitin conjugating enzyme E2 N
Gene Symbol
UBE2N
HGNC ID
HGNC:12492
ORF Size (aa)
459
RefSeq ID
NM_003348
RefSeq Synonyms
NM_003348, BC108704, BC003365, BC000396,
Species
human
UniGene ID
Hs.524630
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.